In general, inter-world relations are peaceful and cooperative. There are minor disagreements between some worlds of course, and occasionally these erupt into short-lived wars. Nothing presently threatens to escalate into a multi-world war. The greatest ongoing hostilities are the constant skirmishes and minor incursions of Ulhuqqa forces into an edge of human- space dominated by humans and Larrokites. Since this is a border region for the Ulhuqqa as well, it is speculated that they are too busy elsewhere in their own space to mount a full-scale invasion. Military planners keep a very careful eye on all activity within this region.
On a smaller scale, most human worlds are controlled by a single political institution, but many are balkanised into discrete political subdivisions. Earth retains many of the historical divisions into separately administrated countries, but is united economically.